Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
Sertraline is a common antidepressant (SSRI) used for depression, anxiety, OCD and related conditions. It works gradually over weeks and should be tapered, not stopped suddenly.
Typical dose — general reference only, NOT a prescription
Measure
Range
Category
Prescription
Adult dose
50 mg once daily (range 25–200 mg); started low and adjusted
Child (paediatric) dose
For OCD in children ≥6 yr under specialist care only
What it is used for
Depression
Anxiety and panic disorder
OCD and PTSD
Some other anxiety-related conditions
Common brand names
India: Serta, Zosert, Daxid, Serlift
Worldwide: Zoloft, Lustral
Common side effects
Nausea, especially early on
Sleep changes
Sexual side effects; early jitteriness
Before taking it — precautions
Full effect takes 4–6 weeks — do not stop early
Do not stop suddenly (taper to avoid withdrawal)
Tell your doctor about other medicines (interactions)
When to see a doctor urgently
Worsening mood or thoughts of self-harm, especially in the first weeks — seek help urgently
Agitation, high fever or confusion (rare serotonin syndrome)
Unusual bleeding
Doses are a general reference, not a prescription. Doses shown are typical adult/paediatric references and vary with age, weight, kidney/liver function and the exact product. Paediatric doses are usually weight-based and must be set by a doctor. MedDroid cannot prescribe — always confirm sertraline and your dose with a doctor or pharmacist and the leaflet inside the pack.
Frequently asked questions
How long does sertraline take to work?
Some effects appear in 1–2 weeks, but the full benefit usually takes 4–6 weeks. Keep taking it and stay in touch with your doctor.
Can I stop sertraline once I feel better?
Not suddenly. Stopping should be gradual and doctor-guided, and treatment often continues for a while after you feel well to prevent relapse.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.