Tamoxifen: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Tamoxifen treats and helps prevent hormone-sensitive breast cancer. It belongs to the Endocrine (cancer hormone) therapy group. These block hormones that drive certain cancers, especially breast cancer.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Endocrine (cancer hormone) therapy
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Hormone-receptor-positive breast cancer, before or after menopause
Lowering the risk of breast cancer returning after surgery
Reducing breast-cancer risk in some high-risk women
Breast cancer in men (hormone-sensitive)

Common brand names

India: Tamodex, Mamofen, Nolvadex
Worldwide: Nolvadex, Soltamox

Common side effects

Hot flushes
Vaginal discharge or irregular periods
Leg cramps
Tiredness or mood changes

Before taking it — precautions

Not used in pregnancy; use non-hormonal contraception
Tell the doctor about past blood clots or stroke
Some antidepressants and other medicines can reduce its effect; check before starting new ones

When to see a doctor urgently

Leg swelling or pain, or sudden breathlessness (clot) (urgent)
Unusual vaginal bleeding or pelvic pain
Sudden weakness, numbness or trouble speaking (urgent)

Not a prescription — no dose shown. The right dose of tamoxifen depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Can tamoxifen be taken before menopause?

Yes. Unlike letrozole or anastrozole, tamoxifen works whether or not you have reached menopause.

Why do I need to report vaginal bleeding?

Tamoxifen slightly raises the risk of womb lining changes, including cancer, so any unusual bleeding should be checked.

Can I get pregnant while on tamoxifen?

You should avoid pregnancy, as it may harm the baby. Use a non-hormonal method and ask how long to wait after stopping.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.