Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
Letrozole lowers oestrogen in breast cancer and is also used to induce ovulation. It belongs to the Endocrine (cancer hormone) therapy group. These block hormones that drive certain cancers, especially breast cancer.
Hormone-sensitive breast cancer (treatment and prevention)
Some other hormone-related conditions
Common brand names
India: Letroz, Femara, Oreta
Worldwide: Femara
Common side effects
Hot flushes
Joint aches (aromatase inhibitors)
Mood changes
Before taking it — precautions
Taken long-term under an oncologist
Bone health is monitored (aromatase inhibitors)
Report unusual bleeding (tamoxifen)
When to see a doctor urgently
Leg swelling/pain or breathlessness (clot with tamoxifen)
Unusual vaginal bleeding
New bone pain or fractures
Not a prescription — no dose shown. The right dose of letrozole depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
How long is breast-cancer hormone therapy taken?
Often 5–10 years, because it greatly lowers the chance of the cancer returning. Your oncologist tailors the duration.
What is the difference between tamoxifen and letrozole?
Tamoxifen blocks oestrogen’s effect and suits many women including before menopause; aromatase inhibitors like letrozole lower oestrogen and are used after menopause.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.