Anastrozole: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Anastrozole is an aromatase inhibitor for breast cancer after menopause. It belongs to the Endocrine (cancer hormone) therapy group. These block hormones that drive certain cancers, especially breast cancer.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Endocrine (cancer hormone) therapy
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Hormone-receptor-positive breast cancer after menopause
Lowering the risk of breast cancer returning after surgery
Sometimes after a period of tamoxifen treatment

Common brand names

India: Anabrez, Armotraz, Arimidex
Worldwide: Arimidex

Common side effects

Joint pain and stiffness
Hot flushes
Tiredness or headache
Vaginal dryness

Before taking it — precautions

Bone density is monitored because it can thin the bones
Not used in pregnancy or before menopause without ovarian suppression
Do not take oestrogen-containing medicines (like HRT) with it

When to see a doctor urgently

New bone pain or a fracture
Severe rash, blisters or swelling of face (urgent)
Yellow skin or eyes

Not a prescription — no dose shown. The right dose of anastrozole depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why do my joints ache on anastrozole?

Low oestrogen often causes joint stiffness. Exercise and simple painkillers may help; tell your doctor if it is severe.

How is anastrozole different from tamoxifen?

Anastrozole lowers oestrogen production and is for women after menopause; tamoxifen blocks oestrogen's effect and works before menopause too.

Can I take HRT for hot flushes?

No, oestrogen in HRT would work against anastrozole. Ask about non-hormonal options.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.