Sofosbuvir: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Sofosbuvir is a direct-acting antiviral that helps cure hepatitis C. It belongs to the HIV & hepatitis antiviral group. These control HIV or viral hepatitis. They are taken long-term (or as a full course) under specialist care.

Ask MedDroid about sofosbuvir →

Drug type — dosing is set by your doctor

Measure	Range
Drug class	HIV & hepatitis antiviral
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Chronic hepatitis C, combined with other antivirals
Hepatitis C of all main genotypes in combination products
Hepatitis C in people with cirrhosis (with specialist care)

Common brand names

India: Hepcinat, Myhep, Sovaldi
Worldwide: Sovaldi, Epclusa (combo)

Common side effects

Tiredness
Headache
Nausea
Trouble sleeping

Before taking it — precautions

Must not be taken with amiodarone; a dangerously slow heartbeat can occur
Hepatitis B is checked first, as it can reactivate
Tell the doctor about all medicines, including St John's wort and some seizure drugs

When to see a doctor urgently

Very slow heartbeat, fainting or chest pain (urgent)
Yellow skin or eyes
Severe breathlessness (urgent)

Not a prescription — no dose shown. The right dose of sofosbuvir depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Can sofosbuvir cure hepatitis C?

Yes. Combined with another antiviral, it cures most people, usually after a course of a few months.

Can I catch hepatitis C again after cure?

Yes, cure does not give immunity, so avoid re-exposure such as shared needles.

Why does it matter if I take amiodarone?

The combination can cause a serious slow heart rhythm, so tell your doctor before starting.

Ask MedDroid about sofosbuvir →

Explore more

Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.