Dolutegravir: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Dolutegravir is a first-line HIV medicine, often in a single combination tablet. It belongs to the HIV & hepatitis antiviral group. These control HIV or viral hepatitis. They are taken long-term (or as a full course) under specialist care.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	HIV & hepatitis antiviral
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

HIV infection, as part of first-line combination treatment
HIV in people who have taken other HIV drugs before
Often given in a single-tablet combination

Common brand names

India: Tivicay, DTG, TLD (combo)
Worldwide: Tivicay

Common side effects

Trouble sleeping or vivid dreams
Headache
Nausea or diarrhoea
Weight gain

Before taking it — precautions

Separate it from antacids, iron, calcium or zinc supplements as advised
Tell the doctor about pregnancy plans and other medicines, including metformin
Report any history of depression

When to see a doctor urgently

Rash with fever, blisters or yellow eyes (urgent)
Low mood or thoughts of self-harm (urgent)
Swelling of face or lips (urgent)

Not a prescription — no dose shown. The right dose of dolutegravir depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Is dolutegravir safe in pregnancy?

Current evidence supports its use in pregnancy, and it is a preferred HIV medicine in many guidelines. Discuss plans with your doctor.

Why must I separate it from supplements?

Calcium, iron, magnesium and antacids can bind it in the gut and stop it working.

Can it cure HIV?

No, but it controls the virus very well, allowing a normal life when taken consistently.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.