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Primaquine: uses, side effects & brands
Primaquine clears the liver stage of vivax malaria to prevent relapse (check G6PD first). It belongs to the Antimalarial (treatment) group. These treat malaria; the choice depends on the malaria type and region.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Antimalarial (treatment) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Clears the hidden liver stage of vivax and ovale malaria to prevent relapse
- Used to stop transmission of falciparum malaria
- Sometimes used with another drug for a type of pneumonia in people with weak immunity
Common brand names
- India: Malirid, Primaquine
- Worldwide: (primaquine brands)
Common side effects
- Tummy cramps or nausea
- Headache
- Dark urine from breakdown of red blood cells in G6PD deficiency
- Bluish lips from methaemoglobin
Before taking it — precautions
- A G6PD blood test is usually done first, because deficiency can cause serious red-cell breakdown
- Not used in pregnancy, and caution in breastfeeding unless the baby is tested
- Tell your doctor about blood disorders or other medicines that affect the blood
When to see a doctor urgently
- Dark or red-brown urine (urgent)
- Sudden paleness, breathlessness, or yellow eyes (urgent)
- Bluish lips or fingertips
Not a prescription — no dose shown. The right dose of primaquine depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Why do I need a G6PD test?
People with G6PD deficiency can have dangerous red-cell breakdown on primaquine, so the test guides safe use.
Why take it after my malaria is treated?
Vivax malaria can hide in the liver and come back months later; primaquine clears this hidden stage.
Should I take it with food?
Taking it with food can reduce stomach upset.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.