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Artemether-Lumefantrine (ACT): uses, side effects & brands
This artemisinin combination (ACT) is first-line for falciparum malaria. It belongs to the Antimalarial (treatment) group. These treat malaria; the choice depends on the malaria type and region.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Antimalarial (treatment) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- First-line treatment of uncomplicated falciparum malaria
- Treats mixed malaria infections
- Used to complete treatment after initial injectable treatment for severe malaria
Common brand names
- India: Lumether, Combither, Coartem
- Worldwide: Coartem, Riamet
Common side effects
- Headache
- Dizziness
- Loss of appetite and nausea
- Weakness or joint and muscle aches
Before taking it — precautions
- Take with fatty food or milk to help it absorb properly
- Tell your doctor about heart rhythm problems or medicines that affect heart rhythm
- Tell your doctor if you are in early pregnancy
When to see a doctor urgently
- Vomiting the dose or inability to keep medicines down (urgent)
- Confusion, fits, drowsiness or breathing difficulty (urgent)
- Fever that returns or does not improve
Not a prescription — no dose shown. The right dose of artemether-lumefantrine depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Why take it with food?
Lumefantrine absorbs much better with fat-containing food or milk, which helps it work.
Does it prevent malaria?
No. It treats malaria and is not used for prevention.
What if I vomit after a dose?
Tell your doctor or pharmacist; the dose may need repeating.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.