Pralidoxime (with atropine): uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Pralidoxime, with atropine, treats poisoning by organophosphate pesticides. It belongs to the Antidote & chelation group. These reverse poisoning, correct overloads or restore clotting.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Antidote & chelation
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Organophosphate pesticide poisoning (with atropine)
Some nerve-agent poisoning
Reversing muscle weakness from these poisons

Common brand names

India: Pam, 2-PAM
Worldwide: Protopam

Common side effects

Blurred vision or double vision
Dizziness and headache
Fast heartbeat
Muscle weakness

Before taking it — precautions

Given only in hospital as an emergency treatment
Works best when started early after poisoning
Dose adjusted in kidney problems

When to see a doctor urgently

Breathing difficulty (urgent)
Seizures or drowsiness (urgent)
Any pesticide swallowing or exposure needs immediate hospital care (urgent)

Not a prescription — no dose shown. The right dose of pralidoxime depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why are atropine and pralidoxime used together?

Atropine controls the dangerous secretions and slow heartbeat, while pralidoxime helps reactivate the enzyme the poison blocks.

What should I do if someone swallows pesticide?

Go to the nearest hospital immediately. Remove contaminated clothes and wash skin; do not wait for symptoms.

Does pralidoxime always work?

It helps most when given early and works better for some pesticides than others. Supportive care is also essential.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.