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Deferasirox: uses, side effects & brands
Deferasirox removes excess iron from repeated blood transfusions. It belongs to the Antidote & chelation group. These reverse poisoning, correct overloads or restore clotting.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Antidote & chelation |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Iron overload from repeated blood transfusions (e.g. thalassaemia)
- Iron overload in some non-transfusion conditions
- Long-term chelation to protect the heart and liver
Common brand names
- India: Asunra, Desirox, Defrijet
- Worldwide: Exjade, Jadenu
Common side effects
- Diarrhoea, nausea or stomach pain
- Skin rash
- Rise in kidney or liver blood tests
Before taking it — precautions
- Regular blood tests of kidney and liver function are needed
- Tell your doctor about stomach ulcers or use of aspirin or anti-inflammatory painkillers
- Avoid antacids containing aluminium at the same time
When to see a doctor urgently
- Black stools or vomiting blood (urgent)
- Yellow skin or eyes, or reduced urine (urgent)
- Severe rash or facial swelling (urgent)
Frequently asked questions
Why is iron overload dangerous?
Extra iron from repeated transfusions builds up in the heart, liver and glands, and can damage them over time.
How is it taken?
It is taken by mouth daily, which many find easier than the older drug deferoxamine given by infusion.
Will I need regular tests?
Yes. Blood tests check iron levels, kidney and liver function, and hearing and eye checks may also be advised.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.