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Hydrocortisone: uses, side effects & brands
Hydrocortisone is a steroid used for adrenal insufficiency, allergy and inflammation. It belongs to the Systemic corticosteroid (extra) group. These steroids strongly reduce inflammation and calm the immune system in many conditions.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Systemic corticosteroid (extra) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Replacement in adrenal insufficiency (Addison's disease)
- Emergency treatment of severe allergic reactions and severe asthma (injection)
- Adrenal crisis
- Inflammatory bowel disease flares and some skin and rectal conditions (creams, foams)
Common brand names
- India: Efcorlin, Lycortin
- Worldwide: Cortef, Solu-Cortef
Common side effects
- Weight gain or increased appetite with higher doses
- Mood changes or poor sleep
- Raised blood sugar
Before taking it — precautions
- In adrenal insufficiency never stop or miss doses; carry a steroid card
- Doses usually need raising during illness or surgery, as your doctor advises
- Tell the doctor about diabetes, infections or stomach ulcers
When to see a doctor urgently
- Vomiting and unable to keep tablets down if you depend on it (urgent)
- Severe weakness, dizziness or fainting (adrenal crisis) (urgent)
- Fever or infection that will not settle
Frequently asked questions
Why do I need more hydrocortisone when I'm sick?
Your body normally makes extra cortisol during illness. If you have adrenal insufficiency, you must copy this by following 'sick-day rules' from your doctor.
Is the hydrocortisone in tablets the same as the cream?
Same steroid, but creams act on the skin and very little reaches the blood.
Will replacement doses cause steroid side effects?
Replacement doses aim to match your natural levels, so side effects are usually few when the dose is right.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.