Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
Glimepiride is a sulfonylurea for type 2 diabetes. It helps the pancreas release more insulin, which lowers blood sugar — but this means it can cause low sugar (hypoglycaemia).
Typical dose — general reference only, NOT a prescription
Measure
Range
Category
Prescription
Adult dose
1–2 mg once daily with breakfast; usual up to 4 mg (max 8 mg/day)
Child (paediatric) dose
Not recommended in children
What it is used for
Type 2 diabetes, often with metformin
When metformin alone is not enough
Common brand names
India: Amaryl, Glimestar, Zoryl, Glimy
Worldwide: Amaryl
Common side effects
Low blood sugar (hypoglycaemia)
Weight gain
Nausea
Before taking it — precautions
Take with breakfast; do not skip meals
Carry a fast sugar source
Caution in the elderly and kidney disease
When to see a doctor urgently
Hypoglycaemia: shakiness, sweating, confusion — take sugar and seek help if severe
Signs of allergy or jaundice
Doses are a general reference, not a prescription. Doses shown are typical adult/paediatric references and vary with age, weight, kidney/liver function and the exact product. Paediatric doses are usually weight-based and must be set by a doctor. MedDroid cannot prescribe — always confirm glimepiride and your dose with a doctor or pharmacist and the leaflet inside the pack.
Frequently asked questions
Why does glimepiride cause low sugar but metformin usually does not?
Glimepiride pushes the pancreas to release insulin regardless of your sugar level, so missing a meal can drop it too low. Metformin works differently and rarely does this alone.
When should I take glimepiride?
Usually just before or with breakfast, so its effect matches your first meal.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.