Duloxetine: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Duloxetine treats depression and anxiety and also helps nerve pain. It belongs to the Antidepressant / anti-anxiety group. These treat depression, anxiety and related conditions, and some also help nerve pain or sleep.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Antidepressant / anti-anxiety
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Depression
Generalised anxiety disorder
Diabetic nerve pain
Fibromyalgia
Chronic musculoskeletal pain

Common brand names

India: Duzela, Dulane, Delok
Worldwide: Cymbalta

Common side effects

Nausea
Dry mouth
Sleep problems or drowsiness
Sweating

Before taking it — precautions

Tell your doctor about liver disease or heavy drinking
It can raise blood pressure; avoid with other serotonin-boosting medicines unless advised
Do not stop suddenly — reduce gradually with your doctor

When to see a doctor urgently

Yellow eyes/skin or dark urine (urgent)
Thoughts of self-harm (urgent)
Confusion, fever, shaking, fast heartbeat (urgent)

Not a prescription — no dose shown. The right dose of duloxetine depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why is duloxetine used for pain?

It changes how pain signals are handled in the spinal cord and brain, which can ease nerve and long-term muscle pain.

Can it raise my blood pressure?

It can raise blood pressure a little in some people, so your doctor may check it.

Can I stop it suddenly?

No — stopping suddenly can cause dizziness, nausea and irritability. Reduce it gradually with your doctor.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.