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Amitriptyline: uses, side effects & brands
Amitriptyline is a tricyclic used in low doses for nerve pain, migraine prevention and sleep. It belongs to the Antidepressant / anti-anxiety group. These treat depression, anxiety and related conditions, and some also help nerve pain or sleep.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Antidepressant / anti-anxiety |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Nerve pain
- Migraine prevention
- Tension headache prevention
- Depression (higher doses)
- Sleep problems with pain
Common brand names
- India: Tryptomer, Amitone
- Worldwide: Elavil
Common side effects
- Drowsiness
- Dry mouth
- Constipation
- Weight gain
Before taking it — precautions
- Tell your doctor about heart problems, glaucoma, prostate problems or epilepsy
- Avoid alcohol and do not drive if drowsy
- Very dangerous in overdose — store safely away from children and others at risk
When to see a doctor urgently
- Fast or irregular heartbeat or fainting (urgent)
- Thoughts of self-harm or suicide (urgent)
- Unable to pass urine or severe constipation
Frequently asked questions
Why is an antidepressant used for pain?
At low doses, amitriptyline calms overactive pain nerves and can help nerve pain and headache prevention, separate from its effect on mood.
Why is it taken at night?
It causes drowsiness, so taking it in the evening can help sleep and reduce daytime grogginess.
Does being prescribed it mean I am depressed?
Not necessarily — it is very often prescribed for pain, migraine prevention or sleep.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.