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Lupus (SLE)
Systemic lupus erythematosus (SLE) is an autoimmune disease where the immune system attacks the body's own tissues. It can affect the skin, joints, kidneys and other organs.
Causes & risk factors
- Autoimmune reaction against the body's tissues
- Genetic predisposition
- Hormonal factors, more common in young women
- Sunlight (UV) exposure triggering flares
- Certain infections or medicines
Common symptoms
- Persistent tiredness
- Joint pain and swelling
- Butterfly-shaped facial rash
- Unexplained fever
- Sensitivity to sunlight
- Hair loss and mouth ulcers
Tests & diagnosis
- ANA (antinuclear antibody)
- Anti-dsDNA antibody
- CBC
- Kidney function test
- ESR
- Urine test for protein
Treatment & management
- Medicines to calm the immune system, as prescribed
- Anti-inflammatory and pain relief for joint symptoms
- Sun protection to prevent flares
- Regular monitoring of kidneys and blood counts
- Managing flares promptly
When to see a doctor urgently
- Persistent fever with joint pain and rash
- Swelling of the legs or reduced urine (kidney involvement)
- Chest pain or breathlessness
- Severe headaches, confusion or seizures
Not a diagnosis. MedDroid gives general educational information about lupus (sle). It cannot examine you, diagnose or prescribe — always confirm with a qualified doctor.
Frequently asked questions
Is lupus contagious?
No. Lupus is an autoimmune disease and cannot be passed from person to person. Its exact cause is not fully understood.
Can people with lupus live a normal life?
Many people with lupus live full lives with treatment. Regular monitoring, sun protection and taking medicines as advised help control the disease.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.