Ursodeoxycholic Acid (UDCA): uses, side effects & brands
Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
UDCA is used for certain gallstones and liver conditions. It belongs to the Liver & miscellaneous group. These support the liver, gallstones or metabolism in specific conditions.
Dissolving small cholesterol gallstones in selected people
Primary biliary cholangitis (a long-term liver condition)
Itching from cholestasis of pregnancy (specialist use)
Preventing gallstones during rapid weight loss
Common brand names
India: Udiliv, Ursocol, Udihep
Worldwide: Ursodiol, Actigall
Common side effects
Loose stools or diarrhoea
Tummy discomfort
Itching
Before taking it — precautions
Does not work on calcified or pigment gallstones
Antacids containing aluminium and some cholesterol medicines reduce absorption; space them
Regular liver blood tests are done
When to see a doctor urgently
Severe right-sided tummy pain, especially with fever (urgent)
Yellow skin or eyes
Severe or persistent diarrhoea
Not a prescription — no dose shown. The right dose of ursodeoxycholic acid depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Can UDCA dissolve all gallstones?
No. It works only on small cholesterol stones in a functioning gallbladder, and it can take many months.
Why is it used in liver disease?
In primary biliary cholangitis it improves bile flow and liver tests, and can slow disease.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.