Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
Tizanidine eases muscle spasm and spasticity. It belongs to the Muscle relaxant group. These ease muscle spasm and stiffness in back pain, neck pain and muscle injuries.
Spasticity from multiple sclerosis or spinal cord injury
Spasticity after stroke or brain injury
Painful muscle spasm (some countries)
Common brand names
India: Sirdalud, Tizan, Brentzo
Worldwide: Zanaflex
Common side effects
Drowsiness
Dry mouth
Dizziness or low blood pressure
Weakness or tiredness
Before taking it — precautions
Do not take with ciprofloxacin or fluvoxamine (they raise its level dangerously)
Tell your doctor about liver or kidney disease or low blood pressure; liver tests may be needed
Do not stop suddenly after regular use; avoid alcohol
When to see a doctor urgently
Fainting or very slow heartbeat (urgent)
Yellow eyes or skin or dark urine
Fast heartbeat and high blood pressure after stopping suddenly
Not a prescription — no dose shown. The right dose of tizanidine depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Why can't I take tizanidine with some antibiotics?
Ciprofloxacin and fluvoxamine block its breakdown and can cause a severe drop in blood pressure and extreme drowsiness.
Why do I feel dizzy on tizanidine?
It can lower blood pressure, especially on standing. Get up slowly.
Can I stop tizanidine suddenly?
No. Stopping suddenly after regular use can cause a rebound rise in blood pressure and heart rate.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.