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Silver Sulfadiazine: uses, side effects & brands
Silver sulfadiazine cream prevents infection in burns. It belongs to the Topical antibiotic group. These treat or prevent infection in minor wounds, burns and skin/eye conditions.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Topical antibiotic |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Preventing infection in burns
- Treating infected burn wounds
- Some other wounds, such as leg ulcers, on medical advice
Common brand names
- India: Silverex, Burnheal, T-Bact SS
- Worldwide: Silvadene, Flamazine
Common side effects
- Burning or pain when applied
- Itching or rash
- Grey-blue skin discolouration with long use
- Temporary fall in white blood cells when used on large areas
Before taking it — precautions
- Not used if you are allergic to sulfa (sulphonamide) medicines
- Not used in late pregnancy, premature babies or newborns
- Tell your doctor about G6PD deficiency, or kidney or liver disease
When to see a doctor urgently
- Severe skin rash, blistering or peeling (urgent)
- Fever, sore throat or frequent infections (possible low white cells)
- Burn showing signs of infection: spreading redness, swelling, bad smell or fever
Frequently asked questions
Should I use it on a small kitchen burn?
Small minor burns are first cooled under running water and covered simply. Larger, deep or blistering burns need a doctor, who may prescribe this cream.
Why has my skin turned greyish?
Silver can deposit in the skin with prolonged use. Tell your doctor.
Can it be used on a baby's burn?
It is not used in newborns or premature babies. Any burn in a baby should be seen by a doctor.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.