Rituximab: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Rituximab treats certain lymphomas and severe autoimmune diseases. It belongs to the Biologic / immunomodulator group. These targeted injectable medicines treat severe autoimmune and allergic diseases by blocking specific immune signals.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Biologic / immunomodulator
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Non-Hodgkin lymphoma and chronic lymphocytic leukaemia
Rheumatoid arthritis
ANCA vasculitis
Some severe autoimmune conditions (e.g. pemphigus)

Common brand names

India: Reditux, Mabtas, Ristova
Worldwide: Rituxan, MabThera

Common side effects

Infusion reactions (fever, chills, rash)
Infections
Tiredness
Low blood counts

Before taking it — precautions

Hepatitis B testing is required; it can reactivate hepatitis B
Given as a hospital drip with pre-medication
Avoid live vaccines; vaccinations may work less well afterwards

When to see a doctor urgently

Breathing difficulty, swelling or collapse during infusion (urgent)
Confusion, weakness or vision loss (rare brain infection) (urgent)
Severe skin blistering or mouth sores (urgent)

Not a prescription — no dose shown. The right dose of rituximab depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why do I get medicines before the drip?

Paracetamol, an antihistamine and often a steroid reduce the chance of an infusion reaction.

How does it work?

It removes B-cells, a type of white cell involved in some lymphomas and autoimmune diseases.

Will my immunity be lower afterwards?

Yes, for months. Report fever or infection promptly and avoid live vaccines.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.