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Prazosin: uses, side effects & brands
Prazosin is an alpha-blocker for blood pressure and nightmares in PTSD. It belongs to the Blood-pressure medicine (extra) group. These lower blood pressure by additional mechanisms, often used when first-line drugs are not enough.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Blood-pressure medicine (extra) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- High blood pressure
- Urine-flow symptoms from an enlarged prostate
- Nightmares in post-traumatic stress disorder (off-label)
- Raynaud's phenomenon (cold, pale fingers)
Common brand names
- India: Minipress XL, Prazopress
- Worldwide: Minipress
Common side effects
- Dizziness or fainting, especially after the first dose
- Drowsiness
- Headache
- Palpitations
Before taking it — precautions
- The first dose is usually taken at bedtime to reduce fainting; stand up slowly
- Before cataract surgery, tell the eye surgeon you take it
- Tell your doctor if you take erection medicines such as sildenafil, as blood pressure can drop too much
When to see a doctor urgently
- Fainting or collapse (urgent)
- Painful erection lasting several hours (urgent)
- Chest pain
Frequently asked questions
Why did I feel dizzy after the first tablet?
Prazosin can cause a sudden drop in blood pressure at the start. Taking the first dose at bedtime and getting up slowly helps.
How does it help nightmares?
It blocks an adrenaline-type signal in the brain linked to nightmares in PTSD; it is used off-label for this.
Can it help prostate symptoms?
Yes, it relaxes muscle in the prostate and bladder neck, easing urine flow.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.