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Piperacillin-Tazobactam: uses, side effects & brands
A broad-spectrum injectable antibiotic for serious infections. It belongs to the Hospital / strong antibiotic (injectable) group. These powerful antibiotics are used in hospital for serious or resistant infections.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Hospital / strong antibiotic (injectable) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Treats serious hospital infections such as pneumonia
- Treats complicated abdominal, urinary, skin and soft-tissue infections
- Used for fever with low white cells in cancer patients
- Covers many resistant bacteria, including Pseudomonas
Common brand names
- India: Piptaz, Zosyn, Tazact
- Worldwide: Zosyn, Tazocin
Common side effects
- Diarrhoea
- Nausea
- Rash
- Pain or irritation at the drip site
Before taking it — precautions
- Tell your doctor if you are allergic to penicillin or other antibiotics
- Tell your doctor about kidney problems, as the dose may need adjusting
- Blood tests may be done during longer courses
When to see a doctor urgently
- Severe or bloody diarrhoea (urgent)
- Allergic reaction such as swelling, wheeze or widespread rash (urgent)
- Unusual bruising or bleeding
Not a prescription — no dose shown. The right dose of piperacillin-tazobactam depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Is this a penicillin?
Yes. Piperacillin is a penicillin, so it must be avoided if you have a penicillin allergy.
What does tazobactam do?
It protects piperacillin from enzymes some bacteria use to destroy antibiotics.
Can it be taken as tablets?
No. It is given only by injection or drip, usually in hospital.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.