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Palonosetron: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed

Palonosetron is a long-acting anti-sickness medicine for chemotherapy. It belongs to the Anti-nausea (chemotherapy) group. These prevent the strong nausea and vomiting caused by chemotherapy or surgery.

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Drug type — dosing is set by your doctor

MeasureRange
Drug classAnti-nausea (chemotherapy)
TypePrescription
DoseIndividual — ask your doctor or pharmacist

What it is used for

Common brand names

Common side effects

Before taking it — precautions

When to see a doctor urgently

Not a prescription — no dose shown. The right dose of palonosetron depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why are several anti-sickness drugs used together for chemo?

Chemotherapy triggers nausea by different pathways, so combining medicines (e.g. an “setron”, aprepitant and a steroid) controls it far better.

How is aprepitant different?

It blocks a specific vomiting signal (NK-1) and is added to prevent the delayed nausea some chemotherapies cause.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.