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Hyaluronic Acid (knee injection): uses, side effects & brands
Hyaluronic acid injections lubricate an arthritic knee joint. It belongs to the Joint & osteoarthritis supplement group. These support joint comfort in osteoarthritis; evidence is modest and they complement, not replace, core care.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Joint & osteoarthritis supplement |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Knee osteoarthritis pain
- When painkillers or exercise have not helped enough
- Delaying or easing symptoms before joint surgery (in some patients)
Common brand names
- India: Synovial, Hyalgan, OSTENIL
- Worldwide: Synvisc, Euflexxa
Common side effects
- Pain or swelling in the knee after injection
- Warmth or stiffness of the joint
- Temporary flare of joint pain
Before taking it — precautions
- Not given if the knee or skin over it is infected
- Tell your doctor about allergy to bird or egg proteins (some products)
- Avoid strenuous activity for a day or two after injection
When to see a doctor urgently
- Hot, red, very painful swollen knee or fever (joint infection) (urgent)
- Facial swelling, rash or breathing difficulty (urgent)
- Severe swelling that does not settle
Frequently asked questions
How does it work?
It adds a gel-like fluid to the knee that may lubricate and cushion the joint for a few months.
How long does it last?
Benefit varies; some people feel better for several months, others notice little difference.
Will it cure my arthritis?
No. It may ease symptoms but does not reverse joint damage.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.