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Evolocumab: uses, side effects & brands
Evolocumab is an injectable PCSK9 inhibitor for very high cholesterol or high risk. It belongs to the Cholesterol & antiplatelet (extra) group. These further lower cholesterol or prevent clots in high-risk people.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Cholesterol & antiplatelet (extra) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Very high LDL cholesterol despite statins
- Familial hypercholesterolaemia (inherited high cholesterol)
- Reducing heart attack and stroke risk in people with heart disease
Common brand names
- India: Repatha
- Worldwide: Repatha
Common side effects
- Redness, pain or bruising at the injection site
- Cold-like symptoms
- Back pain
- Flu-like symptoms
Before taking it — precautions
- Keep taking your other cholesterol medicines unless your doctor says otherwise
- Tell your doctor if you are pregnant or planning pregnancy
- Store as directed (usually in the fridge) and learn the injection technique from your nurse
When to see a doctor urgently
- Severe allergic reaction: swelling of face or throat, difficulty breathing (urgent)
- Widespread rash or hives
- Chest pain or signs of stroke (urgent)
Not a prescription — no dose shown. The right dose of evolocumab depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
How is it given?
It is injected under the skin with a pre-filled pen that you can learn to use at home.
Does it replace my statin?
Usually not. It is most often added to a statin to lower cholesterol further.
How does it work?
It is an antibody that blocks PCSK9, helping the liver remove more LDL cholesterol from the blood.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.