Doxofylline: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Doxofylline is an oral airway opener for asthma and COPD, gentler than theophylline. It belongs to the Bronchodilator & inhaled steroid (extra) group. These open the airways or reduce airway inflammation in asthma and COPD.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Bronchodilator & inhaled steroid (extra)
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Long-term control of wheeze in asthma
COPD
Chronic bronchitis with narrowed airways

Common brand names

India: Doxobid, Synasma, Doxiflo
Worldwide: (doxofylline brands)

Common side effects

Nausea or stomach upset
Headache
Sleeplessness or restlessness
Palpitations

Before taking it — precautions

Tell your doctor about heart disease, irregular heartbeat or high blood pressure
Tell your doctor about stomach ulcers or liver disease
Do not combine with theophylline-type medicines; tell your doctor about antibiotics such as erythromycin

When to see a doctor urgently

Fast or irregular heartbeat (urgent)
Fits or seizures (urgent)
Persistent vomiting

Not a prescription — no dose shown. The right dose of doxofylline depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

How is it different from theophylline?

Unlike theophylline, it has fewer interactions and fewer heart and stomach side effects, and usually needs less blood-level monitoring.

Will it stop a sudden asthma attack?

No. Use your reliever inhaler for sudden symptoms.

Should I limit tea and coffee?

Large amounts of caffeine can add to jitteriness and palpitations, so moderation is sensible.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.