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Chlorpheniramine (CPM): uses, side effects & brands
Chlorpheniramine is an older sedating antihistamine, common in cold and cough combinations. It belongs to the Antihistamine (allergy) group. Antihistamines relieve allergy symptoms such as sneezing, itching, runny nose and hives.
Drug type — dosing is set by your doctor
| Measure | Range |
|---|---|
| Drug class | Antihistamine (allergy) |
| Type | Prescription |
| Dose | Individual — ask your doctor or pharmacist |
What it is used for
- Sneezing and runny nose from allergies or colds
- Itchy skin and hives
- Part of many cold and cough combination medicines
Common brand names
- India: Piriton, CPM, Cadistin
- Worldwide: Chlor-Trimeton, Piriton
Common side effects
- Drowsiness
- Dry mouth
- Blurred vision or constipation
- Dizziness
Before taking it — precautions
- Avoid alcohol and do not drive if drowsy
- Tell your doctor about glaucoma, prostate problems, or epilepsy
- Avoid using several cold medicines together — many already contain it; not for young children unless a doctor advises
When to see a doctor urgently
- Severe allergy (urgent)
- Confusion, hallucinations or seizures (urgent)
- Difficulty passing urine
Frequently asked questions
Why do cold medicines make me sleepy?
Many contain chlorpheniramine, an older antihistamine that causes drowsiness.
Is it safe for children?
Cough and cold combinations should not be given to young children without a doctor's advice.
Can older people take it?
It can cause confusion and urine retention in older people, so newer antihistamines are often preferred.
Explore more
Sources & further reading
- World Health Organization (WHO)
- MedlinePlus — U.S. National Library of Medicine
- Ministry of Health & Family Welfare, India
- Indian Council of Medical Research (ICMR)
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.