Amphotericin B: uses, side effects & brands

Written & medically reviewed by Dr. Sanjay Anbu, MBBS · Last reviewed 5 November 2026

Amphotericin B is a powerful antifungal for severe infections, given in hospital. It belongs to the Antifungal (systemic, advanced) group. These treat serious internal fungal infections and some resistant skin/nail cases.

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Drug type — dosing is set by your doctor

Measure	Range
Drug class	Antifungal (systemic, advanced)
Type	Prescription
Dose	Individual — ask your doctor or pharmacist

What it is used for

Life-threatening fungal infections (e.g. cryptococcal meningitis, invasive candida or mould)
Mucormycosis (black fungus)
Visceral leishmaniasis (kala-azar)

Common brand names

India: Fungizone, Amphotret, Ambisome
Worldwide: AmBisome, Fungizone

Common side effects

Fever, chills and shaking during the drip
Kidney strain
Low potassium and magnesium
Nausea or headache

Before taking it — precautions

Given as a drip in hospital with regular blood tests
Kidney function and salts are closely monitored
Other medicines that strain the kidneys need care

When to see a doctor urgently

Passing very little urine
Severe muscle weakness or irregular heartbeat (urgent)
Breathlessness or swelling during the drip (urgent)

Not a prescription — no dose shown. The right dose of amphotericin b depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.

Frequently asked questions

Why do I shiver during the infusion?

Fever and chills during the drip are common. Staff can slow the drip or give medicines beforehand to reduce them.

What is the difference between lipid and regular amphotericin?

Lipid forms are gentler on the kidneys but more costly. Your doctor chooses based on your situation.

Why is it used for black fungus?

Amphotericin is one of the main drugs that works against mucormycosis, alongside surgery.

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Sources & further reading

Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.