Written & medically reviewed by Dr. Sanjay Anbu, MBBS· Last reviewed
Allopurinol lowers uric acid to prevent gout attacks long-term. It belongs to the Gout medicine group. These lower uric acid to prevent gout, or calm an acute gout attack.
Gout with tophi (uric acid lumps) or kidney stones
Preventing high uric acid during some cancer treatments
Common brand names
India: Zyloric, Ciploric, Zyrik
Worldwide: Zyloprim, Aloprim
Common side effects
Gout flares in the first months of treatment
Skin rash
Nausea or diarrhoea
Abnormal liver tests
Before taking it — precautions
Kidney disease — your doctor will start low and adjust
Never combine with azathioprine or mercaptopurine without your doctor adjusting doses — dangerous interaction
Some people carry a gene (HLA-B*5801) that raises the risk of severe skin reactions; your doctor may test first
When to see a doctor urgently
Any new rash — stop and see a doctor promptly (urgent)
Fever, swollen glands, blistering or peeling skin (urgent)
Yellow skin or eyes
Not a prescription — no dose shown. The right dose of allopurinol depends on age, weight, kidney/liver function and the condition, so MedDroid does not show a dose here. Always get your dose from a doctor or pharmacist and the leaflet inside the pack. General educational information only.
Frequently asked questions
Why did my gout flare after starting allopurinol?
Lowering uric acid can trigger flares at first. Your doctor may add colchicine or a pain reliever for the early months.
Should I stop it during a gout attack?
No — if you are already taking it, keep going and treat the attack separately.
Is it lifelong?
Usually yes — stopping lets uric acid rise again and attacks return.
Reviewed by Dr. Sanjay Anbu, MBBS. MedDroid is an AI medical assistant and can make mistakes. It provides general health information, not a diagnosis or medical advice — always consult a qualified clinician. In an emergency, contact your local emergency number immediately.